Gene Mb1730c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecycA
Gene length1671 bp
IdentifierMb1730c
Location 1915127 bp
Protein summary information
Molecular mass60004.2 Da
Isoelectric point9.9103
Protein length556 amino acids
Orthologs
M. tuberculosis H37RvRv1704c
M. tuberculosis MTBC0mtbc0_001813
Cross-references
UniProtA0A1R3XZW7
InterProIPR002293, IPR004840, IPR004841
UniProtKB/TrEMBLQ7TZR8
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE D-SERINE/ALANINE/GLYCINE TRANSPORTER PROTEIN CYCA
CommentsMb1730c, cycA, len: 556 aa. Equivalent to Rv1704c,len: 556 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 556 aa overlap). Probable cycA,D-serine/D-alanine/glycine transporter, highly similar to P39312|CYCA_ECOLI d-serine/d-alanine/glycine transporter from Escherichia coli (470 aa), FASTA scores: opt: 1906,E(): 0, (59.3% identity in 459 aa overlap); etc. Also similar to other Mycobacterium tuberculosis amino-acid permeases e.g. Rv2127, Rv0346c, etc. Contains PS00218 amino acid permeases signature. BELONGS TO THE AMINO ACID PERMEASE FAMILY (APC FAMILY).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19151271916797-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1730c|cycA
MPDDIAAADPTDTQPHLRRDLANRHIQLIAIGGAIGTGLFMGSGRTISLAGPAVMVVYGIIGFFVFFVLRAMGELLLSNLNYKSFVDFAADLLGPAAGFFVGWSYWFAWVVTGIADLVAITGYARFWWPGLPIWVPALVTVALILAVNLFSVRHFGELEFWFALIKVAAIVCLIAVGAILVATNFVSPHGVHATIENLWNDNGFFPTGFLGVVSGFQIAFFAYIGVELVGTAAAETADPRRTLPRAINAVPLRVAVFYIGALLAILAVVPWRQFASGESPFVTMFSLAGLAAAASVVNFVVVTAAASSANSGFFSTGRMLFGLADEGHAPAAFHQLNRGGVPAPALLLTAPLLLTSIPLLYAGRSVIGAFTLVTTVSSLLFMFVWAMIIISYLVYRRRHPQRHTDSVYKMPGGVVMCWAVLVFFAFVIWTLTTETETATALAWFPLWFVLLAVGWLVTQRRQSRRSFGFHCQVVGVRQQLGRGMARLAMKIHARPKLRSAVVVEPVSAGEPGARRSAKSVRKLASDDSQSAHCPVAVVGLADGGRDPQYHHDGPDR
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