Gene Mb1739 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecmk
Gene length693 bp
IdentifierMb1739
Location 1924940 bp
Protein summary information
Molecular mass24177.3 Da
Isoelectric point4.8299
Protein length230 amino acids
Orthologues
M. tuberculosisRv1712
Cross-references
UniProtP63804
UniProtKB/TrEMBLX2BIX3, P63804
General annotation
TypeCDS
FunctionUnknown
Productcytidylate kinase cmk (cmp kinase) (cytidine monophosphate kinase) (ck)
CommentsMb1739, cmk, len: 230 aa. Equivalent to Rv1712,len: 230 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 230 aa overlap). Probable cmk,cytidylate kinase (EC 2.7.4.14), highly similar to many e.g. KCY_ECOLI|P23863 cytidylate kinase from Escherichia coli (227 aa), FASTA scores: opt: 534, E (): 0, (40.3% identity in 221 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Equivalent to Z95117|MLCB1351_2 from Mycobacterium leprae (223 aa) (73.5% identity in 226 aa overlap). BELONGS TO THE CYTIDYLATE KINASE FAMILY, SUBFAMILY 1.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19249401925632+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1739|cmk
MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR
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