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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GTP-BINDING PROTEIN ENGA
CommentsMb1740, engA, len: 463 aa. Equivalent to Rv1713,len: 463 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 463 aa overlap). Probable engA,GTP-binding protein. Equivalent to Q49884|MLCB1351.01|U00021_5 PROBABLE GTP-BINDING PROTEIN ENGA from Mycobacterium leprae (461 aa), (88.6% identity in 463 aa overlap). And similar to many e.g. P50743|ENGA_BACSU PROBABLE GTP-BINDING PROTEIN ENGA from Bacillus subtilus (436 aa), FASTA scores: opt: 1077, E(): 0, (40.6% identity in 434 aa overlap). Contains two PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ERA/TRME FAMILY OF GTP-BINDING PROTEINS. ENGA SUBFAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19256291927020+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1740|engA
MTQDGTWVDESDWQLDDSEIAESGAAPVVAVVGRPNVGKSTLVNRILGRREAVVQDIPGVTRDRVCYDALWTGRRFVVQDTGGWEPNAKGLQRLVAEQASVAMRTADAVILVVDAGVGATAADEAAARILLRSGKPVFLAANKVDSEKGESDAAALWSLGLGEPHAISAMHGRGVADLLDGVLAALPEVGESASASGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSLIELGGDVWRFVDTAGLRRKVGQASGHEFYASVRTHAAIDSAEVAIVLIDASQPLTEQDLRVISMVIEAGRALVLAYNKWDLVDEDRRELLQREIDRELVQVRWAQRVNISAKTGRAVHKLVPAMEDALASWDTRIATGPLNTWLTEVTAATPPPVRGGKQPRILFATQATARPPTFVLFTTGFLEAGYRRFLERRLRETFGFDGSPIRVNVRVREKRAGKRR
      
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