Gene Mb1765c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenarX
Gene length1959 bp
IdentifierMb1765c
Location 1947625 bp
Protein summary information
Molecular mass72789.4 Da
Isoelectric point9.4752
Protein length652 amino acids
Orthologs
M. tuberculosis H37RvRv1736c
M. tuberculosis MTBC0mtbc0_001849
Cross-references
UniProtA0A1R3XZ78
InterProIPR003765, IPR003816, IPR006656, IPR006963, IPR020945, IPR023234, IPR027467
UniProtKB/TrEMBLQ7VEU1
General annotation
TypeCDS
FunctionUnknown
ProductProbable nitrate reductase NarX
CommentsMb1765c, narX, len: 652 aa. Equivalent to Rv1736c,len: 652 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 652 aa overlap). Probable narX, nitrate reductase (EC 1.7.99.4). Contains three domains: N-terminus (250 aa) is similar to e.g. N-terminus of NARG_ECOLI|P09152 respiratory nitrate reductase 1 alpha chain from Escherichia coli (1246 aa), FASTA scores: E(): 0, (58.6% identity in 251 aa overlap); and Rv1161|MTCI65.28|NARG PROBABLE RESPIRATORY NITRATE REDUCTASE (ALPHA CHAIN) from Mycobacterium tuberculosis (1232 aa). Central region (260-410 aa) is similar to Rv1163|O06561|NARJ PROBABLE RESPIRATORY NITRATE REDUCTASE (DELTA CHAIN) from Mycobacterium tuberculosis (201 aa),FASTA scores: E(): 0, (64.2% identity in 159 aa overlap). C-terminus (420 aa-) is similar to Rv1164|O06562|NARI PROBABLE RESPIRATORY NITRATE REDUCTASE (GAMMA CHAIN) from M. tuberculosis (246 aa), FASTA scores: E(): 0, (68.6% identity in 239 aa overlap). Contains PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19476251949583-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1765c|narX
MTVTPRTGSRIEELLARSGRFFIPGEISADLRTVTRRGGRDGDVFYRDRWSHHKVVRSTHGVNCTGSCSWKIYVKDGIITWETQETDYPSVGPDRPEYEPRGCPRGAAFSWYTYSPTRVRHPYARGVLVEMYREAKARLGDPVAAWADIQADPRRRRRYQRARGKGGLVRVSWAEATEMIAAAHVHTISTYGPDRVAGFSPIPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLPVASPQVFGDQTDVPESGDWWDVVWQCASVLLTYPNSRQLGTAEELLAHIDGPAADLLGRTVSELRRADPLTAATRYVDTFDLRGRATLYLTYWTAGDTRNRGREMLAFAQTYRSTDVAPPRGETPDFLPVVLEFAATVDPEAGRRLLSGYRVPIAALCNALTEAALPYAHTVAAVCRTGDMMGELFWTVVPYVTMTIVAVGSWWRYRYDKFGWTTRSSQLYESRLLRIASPMFHFGILVVIVGHGIGLVIPQSWTQAAGLSEGAYHVQAVVLGSIAGITTLAGVTLLIYRRRTRGPVFMATTVNDKVMYLVLVAAIVAGLGATALGSGVVGEAYNYRETVSVWFRSVWVLQPRGDLMAEAPLYYQIHVLIGLALFALWPFTRLVHAFSAPIGYLFRPYIIYRSREELVLTRPRRRGW
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