Gene Mb1774c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameidi
Gene length531 bp
IdentifierMb1774c
Location 1956859 bp
Protein summary information
Molecular mass19525.2 Da
Isoelectric point7.4541
Protein length176 amino acids
Cross-references
UniProtQ7VEU0
UniProtKB/TrEMBLX2BIB8, Q7VEU0
General annotation
TypeCDS
FunctionUnknown
ProductProbable isopentenyl-diphosphate delta-isomerase IDI (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
CommentsMb1774c, idi, len: 176 aa. Equivalent to Rv1745c,len: 203 aa, from Mycobacterium tuberculosis strain H37Rv,(99.4% identity in 176 aa overlap). Probable idi,isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2),similar to Q46822|ORF_O182 from Escherichia coli (182 aa),FASTA scores: opt: 465, E(): 4.7e-25, (46.9% identity in 162 aa overlap), and to IPPI_SCHPO|Q10132 isopentenyl-diphosphate delta-isomerase from Schizosaccharomyces pombe (227 aa), FASTA scores: opt: 185, E(): 5.4e-06, (30.3% identity in 152 aa overlap). BELONGS TO THE IPP ISOMERASE TYPE 1 FAMILY. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis,truncation at the 3' end due to a single base tranversion (g-t), leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (176 aa versus 203 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19568591957389-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1774c|idi
MTRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVSDLHDQLLITRRAATKRTWPAVWTNSCCGHPLPGESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGTVENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVTAGVIAPVSPWCRSQLG
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