Gene Mb1780
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE OXIDOREDUCTASE |
| Comments | Mb1780, -, len: 460 aa. Equivalent to Rv1751, len: 460 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 460 aa overlap). Probable oxidoreductase (EC 1.-.-.-), possibly a monooxygenase or hydroxylase, similar to MHPA_ECOLI|P77397 3-(3-hydroxy-phenyl) propionate hydroxylase (554 aa),FASTA scores: opt: 239, E(): 2e-08, (24.6% identity in 435 aa overlap); and AJ007932|SAR7932.13 oxygenase from Streptomyces argillaceus (436 aa), FASTA scores: opt: 587,E(): 8.6e-30, (32.3% identity in 359 aa overlap). Contains PS00075 Dihydrofolate reductase signature. Also similar to Mycobacterium tuberculosis hypothetical oxidoreductases Rv1260 and Rv0575c. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1965019 | 1966401 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1780|Mb1780
MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMGETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTTMRLLDELGLWERFAALPYSEVRTATLHSNGRAVTYIDFERLHQPYPYVAMVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLREGGKVTGVRYQGAEGPGELRAELTVACDGRWSIARHEAGLKAREFPVNFDVWWFKLPREGDAEFSFLPRFSPGKGLGVIPREGYFQIAYLGPKGTDAQLRERGIEEFRRDVSELLPEATASVAALASTDEVKHLNVKVNRLRRWHIDGLLCIGDAAHAMSPVAGVGINLAVQDAVAAATILAEPLREHRVSSRHLAAVRRRRAFPTAVTQAVQRVLHRRLLGPLLQGRDPTPPAALLGLVERLPWLSAVPAYFVGVGVRPEHAPAFARRGPGNRKGP
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