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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHOLIPASE C 4 PLCD
CommentsMb1784c, plcD, len: 514 aa. Equivalent to MT1799,len: 514 aa, from Mycobacterium tuberculosis strain CDC1551, (100% identity in 514 aa overlap). Probable plcD,phospholipase C 4 (EC 3.1.4.3) (see citation below),highly similar to other phospholipases e.g. Q04001|PHLA_MYCTU|Rv2351c|PLCA|MTP40|MT2416|MTCY98.20c PROBABLE MEMBRANE-ASSOCIATED PHOSPHOLIPASE C 1 PLCA from Mycobacterium tuberculosis (512 aa), FASTA score: opt: 2657, E(): 4.9e-156, (71.1% identity in 512 aa overlap); P95246|PHLB_MYCTU|PLCB|MPCB|Rv2350c|MT2415|MTCY98.19c PROBABLE MEMBRANE-ASSOCIATED PHOSPHOLIPASE C 2 PLCB from Mycobacterium tuberculosis (512 aa), FASTA score: opt: 2638, E(): 7.3e-155, (70.9% identity in 512 aa overlap); etc. BELONGS TO THE BACTERIAL PHOSPHOLIPASE C FAMILY. REMARK-M.bovis-M.tuberculosis: No equivalent in Mycobacterium tuberculosis strain H37Rv. Belong to RvD2 region.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19722461973790-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1784c|plcD
MSQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC
      
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