Gene Mb1802c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1802c
Gene length747 bp
IdentifierMb1802c
Location 1997478 bp
Protein summary information
Molecular mass26632.5 Da
Isoelectric point8.2591
Protein length248 amino acids
Orthologues
M. tuberculosisRv1773c
Cross-references
UniProtA0A1R3XZM4
InterProIPR005471, IPR011991, IPR014757
UniProtKB/TrEMBLQ7TZK5
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsMb1802c, -, len: 248 aa. Equivalent to Rv1773c,len: 248 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 248 aa overlap). Probable transcriptional regulator belonging to IclR family,similar to ICLR_ECOLI|P16528 acetate operon repressor from Escherichia coli (274 aa), FASTA scores: opt: 261, E(): 3.3e-10, (26.9% identity in 249 aa overlap). Also similar to Mycobacterium tuberculosis protein Rv1719|MTCY04C12.04 (40.2% identity in 244 aa overlap); and Rv2989. Start site chosen by homology, but may extend further upstream. Contains possible helix-turn-helix motif at aa 37-58 (+3.24 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19974781998224-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1802c|Mb1802c
MPPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSVDSHGRFALGERLLGFGSVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDDADAEAALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRALGDNVIAISVPAPTARFLEKEQRIIAALRAAADSPDWTR
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