Gene Mb1806 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecyp144
Gene length1305 bp
IdentifierMb1806
Location 2001114 bp
Protein summary information
Molecular mass47209.9 Da
Isoelectric point4.9131
Protein length434 amino acids
Cross-references
UniProtA0A1R3XZA3
InterProIPR001128, IPR002397, IPR017972
UniProtKB/TrEMBLQ7VET9
General annotation
TypeCDS
FunctionUnknown
ProductProbable cytochrome p450 144 CYP144
CommentsMb1806, cyp144, len: 434 aa. Equivalent to Rv1777,len: 434 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 434 aa overlap). Probable cyp144,cytochrome p450 (EC 1.14.-.-), similar to CPXM_BACME|Q06069 cytochrome p450 (meg) (EC 1.14.99.-) (410 aa), FASTA scores: opt: 435 E(): 2.3e-16, (28.8% identity in 372 aa overlap). Also similar to several other Mycobacterium tuberculosis p450 genes including Rv0766c,Rv2266, etc. Contains PS00086 Cytochrome P450 cysteine heme-iron ligand signature. BELONGS TO THE CYTOCHROME P450 FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20011142002418+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1806|cyp144
MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGQYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ
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