Gene Mb1815 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE25
Gene length1095 bp
IdentifierMb1815
Location 2015759 bp
Protein summary information
Molecular mass36961.2 Da
Isoelectric point10.0264
Protein length364 amino acids
Orthologs
M. tuberculosis H37RvRv1787
M. tuberculosis MTBC0mtbc0_001900
Cross-references
UniProtA0A1R3XZC3
InterProIPR000030, IPR022171
UniProtKB/TrEMBLQ7TZJ5
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe25
CommentsMb1815, PPE25, len: 364 aa. Equivalent to Rv1787,len: 365 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 365 aa overlap). Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, similar to Z74024|MTCY274.24 Mycobacterium tuberculosis cosmid (404 aa), FASTA scores: opt: 837, E(): 0, (52.0% identity in 406 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 8 bp to 5 bp substitution (agcccggt-ccggg), leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (364 aa versus 365 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20157592016853+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1815|PPE25
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTEPGAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG
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