Gene Mb1832c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS32a
Gene length264 bp
IdentifierMb1832c
Location 2037034 bp
Protein summary information
Molecular mass8824.06 Da
Isoelectric point4.4216
Protein length87 amino acids
Orthologs
M. tuberculosis H37RvRv1803c
Cross-references
UniProtA0A1R3XZQ3
InterProIPR000084
UniProtKB/TrEMBLQ7TZI2
General annotation
TypeCDS
FunctionUnknown
ProductPE-PGRS FAMILY PROTEIN [FIRST PART]
CommentsMb1832c, PE_PGRS32a, len: 87 aa. Equivalent to 5' end of Rv1803c, len: 639 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 87 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins. Most similar to Rv1768|MTCY28.34|Z95890 (618 aa), FASTA scores: opt: 1827, E( ): 0, (53.5% identity in 664 aa overlap). Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PE_PGRS32 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base transition (c-t) splits PE_PGRS32 into 2 parts, PE_PGRS32a and PE_PGRS32b, with PE_PGRS32a being truncated.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20370342037297-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1832c|PE_PGRS32a
MWTSQMIVAPAFVDAAAKDLATIGSAISRANAEALVPITALLPAGADDVSAAIAALFATHGQAYQELSAHAVAFHEQFVQLMSAGAA
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