Gene Mb1908
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [FIRST PART] |
| Comments | Mb1908, -, len: 511 aa. Similar to 5' end of Rv1877, len: 687 aa, from Mycobacterium tuberculosis strain H37Rv, (93.2% identity in 292 aa overlap). Probable conserved integral membrane protein, part of major facilitator superfamily (MFS), similar to many antibiotic and drug efflux proteins. Similar to e.g. Q56175 TU22 DTDP-GLUCOSE DEHYDRTATASE from Streptomyces violaceoruber (557 aa), FASTA scores: opt: 895, E(): 0, (34.7% identity in 528 aa overlap). Also similar to Mycobacterium tuberculosis relatives protein, include Rv3728, Rv3239c,Rv2846c, etc. Contains PS00217 Sugar transport proteins signature 2 (PS00217). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv1877 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion (*-c), splits Rv1877 into 2 parts,Mb1908 and Mb1909. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2116113 | 2117648 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1908|Mb1908
MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPALPTIVAELGSTVDQSWAVTSYLLGGTVVVVVAGKLGDLLGRNRVLLGSVVVFVVGSVLCGLSQTMTMLAISRALQGVGAGAISVTAYALAAEVVPLRDRGRYQGVLGAVFGVNTVTGPLLGGWLTDYLSWRWAFWINVPVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTYAWGSATIVGLLIGAAVALGFFVWLEGRARCGHPAAQAVWQPSICRVLRPVLRGRIRDAGCTDLRTDLSGVRGRRVGDRVRSAHVADGDRPADRLDRDGCPGRPDGPLQDLPGRGDGADGGCVPADVADGRVDATAAAIAVPGRPRCRHRIVHAGARSHRAEHVVFRRPRRRNIGCDLLPGGRRLVWYRNIRCVVRKLPGPKTRFRADVGRRACPGSAISGCLASAAPEHGRPDRAGICRVAHPGVPLRGLGHGGRFHPGAVAARGTAHRHPR
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