Gene Mb1967 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametpx
Gene length498 bp
IdentifierMb1967
Location 2175007 bp
Protein summary information
Molecular mass16896.1 Da
Isoelectric point4.1212
Protein length165 amino acids
Orthologues
M. tuberculosisRv1932
Cross-references
UniProtP66953
UniProtKB/TrEMBLX2BJP5, P66953
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE THIOL PEROXIDASE TPX
CommentsMb1967, tpx, len: 165 aa. Equivalent to Rv1932,len: 165 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 165 aa overlap). Probable tpx (alternate gene name: cfp20), thiol peroxidase (EC 1.11.1.-) similar to TPX_ECOLI|P37901 thiol peroxidase (EC 1.11.1.-) (p20) from Escherichia coli (167 aa), fasta scores: opt: 535, E(): 7.3e-25, (52.4% identity in 164 aa overlap). There are four other related enzymes in M. tuberculosis: Rv2428, Rv2521, Rv2238c, Rv1608c.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21750072175504+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1967|tpx
MAQITLRGNAINTVGELPAVGSPAPAFTLTGGDLGVISSDQFRGKSVLLNIFPSVDTPVCATSVRTFDERAAASGATVLCVSKDLPFAQKRFCGAEGTENVMPASAFRDSFGEDYGVTIADGPMAGLLARAIVVIGADGNVAYTELVPEIAQEPNYEAALAALGA
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