Gene Mb1970c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameechA13
Gene length957 bp
IdentifierMb1970c
Location 2177838 bp
Protein summary information
Molecular mass35250.0 Da
Isoelectric point6.9975
Protein length318 amino acids
Orthologues
M. tuberculosisRv1935c
Cross-references
UniProtA0A1R3XZR7
InterProIPR001753
UniProtKB/TrEMBLI3NIF9
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ENOYL-COA HYDRATASE ECHA13 (ENOYL HYDRASE) (UNSATURATED ACYL-COA HYDRATASE) (CROTONASE)
CommentsMb1970c, echA13, len: 318 aa. Equivalent to Rv1935c, len: 318 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 318 aa overlap). Possible echA13, enoyl-CoA hydratase (EC 4.2.1.17),similar to others and various enzymes e.g. CAC48381.1|Y16952 putative enoyl-CoA-isomerase from Amycolatopsis mediterranei (269 aa); AAK18173.1|AF290950_5|AF290950|FadB1x enoyl-CoA hydratase from Pseudomonas putida (257 aa); AAF78820.1|AF042490 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. TM1 (276 aa); ECHM_RAT|P14604 enoyl-coa hydratase mitochondrial precursor from Rattus norvegicus (Rat) (290 aa), FASTA scores: opt: 228, E( ): 1.2e-08, (31.0% identity in 258 aa overlap); etc.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21778382178794-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1970c|echA13
MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNAQTRGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRERSPGPDQHPSYRCNGATFGGVESRNRQEWHYYFENTKRWRNLRKITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFGHPWEFGPRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPTMAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTVEYGLEDWRAAPQIRPAIKQRP
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