Gene Mb1973 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameephB
Gene length1071 bp
IdentifierMb1973
Location 2182662 bp
Protein summary information
Molecular mass39297.4 Da
Isoelectric point4.8785
Protein length356 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_002052
M. tuberculosis H37RvRv1938
Cross-references
UniProtA0A1R3XZT6
InterProIPR000073, IPR000639
UniProtKB/TrEMBLQ7TZ94
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE HYDRATASE)
CommentsMb1973, ephB, len: 356 aa. Equivalent to Rv1938,len: 356 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 356 aa overlap). Probable ephB,epoxide hydrolase (EC 3.3.2.3) (see citation below),similar to many e.g. G1109600 ATSEH (EC 3.3.2.3) (321 aa),FASTA scores: opt: 442, E(): 1.2e-21 (33.1% identity in 356 aa overlap); etc. Also similar to many other M. tuberculosis hypothetical epoxide hydrolases e.g. Rv3617,Rv3670, Rv0134, etc.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21826622183732+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1973|ephB
MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP
Bibliography
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