Gene Mb2040 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2040
Gene length1041 bp
IdentifierMb2040
Location 2242914 bp
Protein summary information
Molecular mass38663.3 Da
Isoelectric point6.9274
Protein length346 amino acids
Orthologues
M. tuberculosisRv2017
Cross-references
UniProtA0A1R3Y0C4
InterProIPR001387, IPR010359, IPR010982
UniProtKB/TrEMBLQ7VET2
General annotation
TypeCDS
FunctionUnknown
Producttranscriptional regulatory protein
CommentsMb2040, -, len: 346 aa. Equivalent to Rv2017, len: 346 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 346 aa overlap). Hypothetical regulatory protein, shows similarity at N-terminal end to several transcriptional regulators e.g. Bacillus subtilis BSUB0012_44 (108 aa). Contains PS00142 Neutral zinc metallopeptidases, zinc-binding region signature in C-terminal half, may be fortuitous. FASTA scores: Z99115|BSUB0012_44 Bacillus subtilis (108 aa) opt: 154,E(): 0.0012; 35.5% identity in 62 aa overlap. Contains probable helix-turn-helix motif at aa 18-39 (Score 2243,+6.83 SD)
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22429142243954+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2040|Mb2040
MNGLGDVLAVARKARGLTQIELAELVGLTQPAINRYESGDRDPDQHIVAKLAEILGVTDDLLIHGNRFRGALAVDAHMRRHKTTKASAWRQLEARLNLLRVHASFLFEEVAINSEQHVPAFDPEFTAAEDAARLVRAQWRMPMGPVVNLTRWMEAAGCLVFEEDFATQRIDGLSQWVDDYPVMLINANAAPDRKRLTLAHELGHLVLHSTNPTENMETEATAFAAEFLMPESEIRPELRRLDLGKLLELKREWGVSMQALLERAYRMGLVSAEARTKLYKAMNARGWKTKEPGIESIVREKPSLPAHIGMTLRSRGFTDQQAAAIAGYANPADNPFRPEGGRLHAI
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