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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productconserved membrane protein
CommentsMb2050c, -, len: 332 aa. Equivalent to Rv2025c,len: 332 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 332 aa overlap). Possible conserved transmembrane protein, CDF family possibly involved in transport of metal ions, similar to several hypothetical bacterial proteins e. g. Methanobacterium thermoautotrophicum AE000941_1 (298 aa; described as cation efflux system protein) and Archaeoglob us fulgidus AE001111_5 (384 aa). FASTA scores: AE000941_1 M ethanobacterium thermoautotrophicum (298 aa) opt: 452 E(): 3.3e-24; 30.8% identity in 266 aa overlap and AE001111_5 Archaeoglobus fulgidus section 16 (384 aa) opt: 371 E(): 1.7e-18; 27.7% identity in 267 aa overlap. TBparse score is 0.897
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22546642255662-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2050c|Mb2050c
MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGGVALGFPLADPIVGLLITAAILAVLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE
      
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