Gene Mb2052c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedost
Gene length1722 bp
IdentifierMb2052c
Location 2256701 bp
Protein summary information
Molecular mass62154.6 Da
Isoelectric point4.6203
Protein length573 amino acids
Orthologues
M. tuberculosisRv2027c
Cross-references
UniProtA0A1R3Y037
InterProIPR003018, IPR003594, IPR011712
UniProtKB/TrEMBLQ7VET1
General annotation
TypeCDS
FunctionUnknown
Producttwo component sensor histidine kinase dost
CommentsMb2052c, -, len: 573 aa. Equivalent to Rv2027c,len: 573 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 573 aa overlap). Membrane protein related to histidine kinase response regulators. Highly similar to Mycobacterium tuberculosis protein Rv3132c,MTCY03A2.2 6. FASTA scores: Z83867|MTCY3A2_26 (578 aa) opt: 2330, E(): 0; 62.5% identity in 560 aa overlap.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22567012258422-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2052c|dost
MTHPDRANVNPGSPPVRETLSQLRLRELLLEVQDRIEQIVEGRDRLDGLIDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPAMVFRLIAEEALTLMAGAATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVFHDRTPRRFDRLDLAVDGPVEPGPALVLPLRAADTVAGVLVALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQRQMREVEILTDRDRIARDLHDHVIQRLFAVGLTLQGAAPRARVPAVRESIYSSIDDLQEIIQEIRSAIFDLHAGPSRATGLRHRLDKVIDQLAIPALHTTVQYTGPLSVVDTVLANHAEAVLREAVSNAVRHANATSLAINVSVEDDVRVEVVDDGVGISGDITESGLRNLRQRADDAGGEFTVENMPTGGTLLRWSAPLR
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