Gene Mb2054c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepfkB
Gene length1020 bp
IdentifierMb2054c
Location 2259319 bp
Protein summary information
Molecular mass35401.4 Da
Isoelectric point5.6648
Protein length339 amino acids
Orthologs
M. tuberculosis H37RvRv2029c
M. tuberculosis MTBC0mtbc0_002162
Cross-references
UniProtA0A1R3XZZ1
InterProIPR002173, IPR011611, IPR017583
UniProtKB/TrEMBLQ7TZ43
General annotation
TypeCDS
FunctionUnknown
Product6-phosphofructokinase pfkb (phosphohexokinase) (phosphofructokinase)
CommentsMb2054c, pfkB, len: 339 aa. Equivalent to Rv2029c,len: 339 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 339 aa overlap). Probable pfkB,phosphofructokinase (EC 2.7.1.-), similar to others eg P06999|K6P2_ECOLI 6-PHOSPHOFRUCTOKINASE I SOZYME 2 from E. coli (309 aa), FASTA scores: opt: 705, E(): 0; (41.4% identity in 304 aa overlap); and LACC_STRMU phosphotagatosekinase (310 aa); etc. Contains PS00583 pfkB family of carbohydrate kinases signature 1.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22593192260338-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2054c|pfkB
MTEPAAWDEGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPRYDPGGGGINVARIVHVLGGCSTALFPAGGSTGSLLMALLGDAGVPFRVIPIAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAASAAFVVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSGVFLLKASVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGALLATRHASHRFSSIPMTAVSGVGAGDAMVAAITVGLSRGWSLIKSVRLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNPEASP
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