Gene Mb2057c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehspX
Gene length435 bp
IdentifierMb2057c
Location 2262411 bp
Protein summary information
Molecular mass16227.3 Da
Isoelectric point4.7523
Protein length144 amino acids
Orthologs
M. tuberculosis H37RvRv2031c
M. tuberculosis MTBC0mtbc0_002164
Cross-references
UniProtP0A5B8
UniProtKB/TrEMBLX2BJK6, P0A5B8
General annotation
TypeCDS
FunctionUnknown
Productheat shock protein hspx (alpha-crystallin homolog) (14 kda antigen) (hsp16.3)
CommentsMb2057c, hspX, len: 144 aa. Equivalent to Rv2031c,len: 144 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 144 aa overlap). hspX, heat shock protein localized in the inner membrane (see citations below). Identical to P30223|14KD_MYCTU 14 KD ANTIGEN (16 kDa ANTIGEN) (HSP 16.3) of Mycobacterium tuberculosis (143 aa), FASTA scores: opt: 933, E(): 0, (100.0% identity in 143 aa overlap). BELONGS TO THE SMALL HEAT SHOCK PROTEIN (HSP20) FAMILY. Also known as alpha-crystallin and gene as acr (see some citations below). TBparse score is 0.897.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22624112262845-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2057c|hspX
MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMKEGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDGRSEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGKPTEKHIQIRSTN
Bibliography
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