Gene Mb2058 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameacg
Gene length996 bp
IdentifierMb2058
Location 2263042 bp
Protein summary information
Molecular mass36575.4 Da
Isoelectric point5.2284
Protein length331 amino acids
Orthologs
M. tuberculosis H37RvRv2032
M. tuberculosis MTBC0mtbc0_002165
Cross-references
UniProtA0A1R3Y0T1
InterProIPR000415
UniProtKB/TrEMBLQ7VET0
General annotation
TypeCDS
FunctionUnknown
Productconserved protein acg
CommentsMb2058, -, len: 331 aa. Equivalent to Rv2032, len: 331 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 331 aa overlap). acg (for acr-coregulated gene), conserved hypothetical protein possibly member of a superfamily of classical nitroreductases (see first citation below), similar to hypothetical mycobacterial proteins Rv3127|MTCY164.37 (344 aa) and Rv3131|MTCY03A2.27c (332 aa). FASTA scores: Z95150|MTCY164_38 Mycobacterium tuberculosis cosmid (344 aa) opt: 1208, E(): 0, (56.4% identity in 321 aa overlap); Z83867| MTCY3A2_27 Mycobacterium tuberculosis cosmid (332 aa) opt: 568, E(): 8.6e-30, (36.8% identity in 321 aa overlap). Similar to proteins SCJ1.11 (330 aa; AL109962) and SCJ12.27c (335 aa; AL109989) in Streptomyces coelicolor.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22630422264037+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2058|acg
MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRPELAAASKLTESLRLYDSSYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLSTYDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVRVGLAPEMEEPPPATPRRLIDEVFHVRAKDHR
Bibliography
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