Gene Mb2096c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecobK
Gene length696 bp
IdentifierMb2096c
Location 2311404 bp
Protein summary information
Molecular mass24580.5 Da
Isoelectric point9.8919
Protein length231 amino acids
Orthologs
M. tuberculosis H37RvRv2070c
Cross-references
UniProtA0A1R3Y042
InterProIPR003723
UniProtKB/TrEMBLQ7VER6
General annotation
TypeCDS
FunctionUnknown
Productprecorrin-6x reductase cobk
CommentsMb2096c, cobK, len: 231 aa. Similar to Rv2070c,len: 244 aa, from Mycobacterium tuberculosis strain H37Rv,(98.7% identity in 227 aa overlap). Probable cobK,precorrin-6x reductase (EC 1.3.1.54), similar to e.g. L21196|g347169|RERCOBLMK3 RERCOBLMKN from Rhodococcus sp. NI86/21 (248 aa), FASTA scores: opt: 792, E(): 0, (53.6% identity in 250 aa overlap). Also similarity to CBIJ_SALTY|Q05591 cbij protein from Salmonella typhimurium (263 aa), FASTA scores: opt: 166, E(): 9e-0 5, (26.7% identity in 258 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base insertion (*-a) leads to a shorter product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (231 aa versus 244 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23114042312099-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2096c|cobK
MRWRKSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
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