Gene Mb2097c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecobM
Gene length756 bp
IdentifierMb2097c
Location 2312136 bp
Protein summary information
Molecular mass26438.5 Da
Isoelectric point6.1127
Protein length251 amino acids
Cross-references
UniProtA0A1R3Y2A3
InterProIPR000878, IPR003043, IPR006362, IPR014776, IPR014777
UniProtKB/TrEMBLQ7VER5
General annotation
TypeCDS
FunctionUnknown
Productprecorrin-3 methylase cobm (precorrin-4 c11-methyltransferase)
CommentsMb2097c, cobM, len: 251 aa. Equivalent to Rv2071c,len: 251 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 251 aa overlap). Probable cobM,precorrin-3 methylase (EC 2.1.1.133), similar to e.g. L21196|g347169|RERCOBLMK2 RERCOBLMK from Rhodococococcus sp. NI86/21 (249 aa), FASTA scores: opt: 992, E(): 0,(62.4% identity in 245 aa overlap) and to COBM_ PSEDE|P21922 precorrin-3 methylase (253 aa), FASTA scores: opt: 863, E(): 0, (54.6% identity in 249 aa overlap). Contains PS00839 Uroporphyrin-III C-methyltransferase signature 1, and PS00840 Uroporphyrin-III C-methyltransferase signature 2.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23121362312891-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2097c|cobM
MTVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLEQIVRKLADADADGRDVARLHSGDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAALKRELTVPGVAQTVTLTRVATLSTPMPPGEDLAALARSRATLVLHLAAAQIDAIVPRLLDGGYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYLYSVARHGRYAQ
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