Gene Mb2117
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable 5'-3' exonuclease |
| Comments | Mb2117, -, len: 374 aa. Equivalent to Rv2090, len: 393 aa, from Mycobacterium tuberculosis strain H37Rv,(94.7% identity in 393 aa overlap). Probable 5'-3' exonuclease, similar to exonuclease part of DNA polymerase, e.g. DPO1_MYCTU Q07700 DNA polymerase I (EC 2.7.7.7) (pol i) (904 aa), FASTA scores, opt: 461, E(): 1.2e-17, (38.7% identity in 292 aa overlap). BELONGS TO FAMILY A OF DNA POLYMERASES. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 57 bp in-frame deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (374 aa versus 393 aa). |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2329273 | 2330397 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2117|Mb2117
MPAPDPMRGDPPHPAPPRLRSPLDPTSGDPLHPAPPRLRSPLDPTSGDPLHPAPPRLRSPLVLLDGASMWFRSFFGVPSSITAPDGRPVNAVRGFIDSMAVVIIQQRPNRLAVCLDLDWRPQFRVDLIPSYKAHRVAEPEPNGQPDVEEVPDELTPQVDMIMELLDAFGIAMAGAPGFEADDVLGTLATRERRDPVIVVSGDRDLLQVVADDPVPVRVLYLGRGLAKATLFGPAEVAERYGLPAHRAGAAYAELALLRGDPSDGLPGVPGVGEKTAATLLARHGSLDQIMAAADDRKTTMAKGLRTKLLAASAYIKAADRVVRVATDAPVTLSTPTDRLPLVAADPERTAELATRFGVESSIARLQKALDTLPG
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