Gene Mb2122c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepafc
Gene length951 bp
IdentifierMb2122c
Location 2335208 bp
Protein summary information
Molecular mass33792.5 Da
Isoelectric point4.4323
Protein length316 amino acids
Orthologues
M. tuberculosisRv2095c
Cross-references
UniProtA0A1R3Y0A3
InterProIPR026881, IPR028349
UniProtKB/TrEMBLQ7TZ19
General annotation
TypeCDS
FunctionUnknown
Productproteasome accessory factor c pafc
CommentsMb2122c, -, len: 316 aa. Equivalent to Rv2095c,len: 316 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 316 aa overlap). Conserved hypothetical protein. Highly similar to ML1330 P54075|YY35_MYCLE HYPOTHETICAL 27.0 KD PROTEIN (247 aa) opt: 1127 E(): 0,(78.4% identity in 227 aa overlap). Also similar to ORF11(1) of Rhodococcus erythropolis. FASTA score: Z82004|REZ820043 REZ82004 NID: g1666179 - Rhodococcus (326 aa) opt: 624 E(): 1.1e-30; (56.7% identity in 319 aa overlap). Contains possible helix-turn-helix motif at aa 25-46, ( +2.92 SD)
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23352082336158-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2122c|pafc
MSALSTRLVRLLNMVPYFQANPRITRAEAAAELGVTAKQLEEDLNQLWMCGLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALADIPGVVDPQAARSAIAKIAAAAGAVAAVAEQAPTESPAAAAVRAAVRNSRALTIDYYAASHDTLTTRIVDPIRVLLIGGHSYLEAWSREAEGVRLFRFDRIVDAAELGEPAVPPESARQAPPDTSLFDGDLSLPSATLRVAPSASWMLEYYPIRELRQLPDGSCEVVMTYASEDWMTRLLLGFGSDVRVLAPESLAQRVRDAATAALDAYQAAAPP
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