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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs36
CommentsMb2125c, PE_PGRS36, len: 491 aa. Equivalent to Rv2099c (PE21) and Rv2098c (PE_PGRS36), len: 58 aa and 433 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 58 aa overlap and 99.8% identity in 433 aa overlap). Rv2098c|PE_PGRS36: Member of Mycobacterium tuberculosis PE-family, PGRS sub-family. Frameshifted near N-terminus. Rv2099c|PE21: 5'-end of Rv2098c (MTCY49.38c),then frameshifts. Sequence has been checked, no errors found. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PE_PGRS36 and PE21 exist as 2 genes. In Mycobacterium bovis, a single base insertion (*-c) leads to a single product more similar to PE_PGRS36. There is also a 3 bp in-frame deletion (ggc-*).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23385722340047-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2125c|pe21
MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAAAFHDRFVQLLNAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSAGLIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHGGSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLGARLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPGGSGGNGGVWYGNGGAGGAAGQGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLLFGVPGPSGPDG
      
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