Gene Mb2145c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehisG
Gene length855 bp
IdentifierMb2145c
Location 2360231 bp
Protein summary information
Molecular mass30480.8 Da
Isoelectric point4.7128
Protein length284 amino acids
Orthologs
M. tuberculosis H37RvRv2121c
M. tuberculosis MTBC0mtbc0_002253
Cross-references
UniProtP60760
UniProtKB/TrEMBLX2BK72, P60760
General annotation
TypeCDS
FunctionUnknown
Productatp phosphoribosyltransferase hisg
CommentsMb2145c, hisG, len: 284 aa. Equivalent to Rv2121c,len: 284 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 284 aa overlap). Probable hisG, ATP phosphoribosyltransferase (EC 2.4.2.17) (see citation below), similar to others e.g. HIS1_ECOLI|P10366 ATP phosphoribosyltransferase from Escherichia coli (299 aa),FASTA scores: opt: 351, E(): 4.5e-20, (31.8% identity in 289 aa overlap); etc.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23602312361085-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2145c|hisG
MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAPLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
Bibliography
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