Gene Mb2147 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE37
Gene length1395 bp
IdentifierMb2147
Location 2361496 bp
Protein summary information
Molecular mass47641.3 Da
Isoelectric point5.4882
Protein length464 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_002255
M. tuberculosis H37RvRv2123
Cross-references
UniProtA0A1R3Y2D4
InterProIPR000030
UniProtKB/TrEMBLQ7VEQ6
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe37
CommentsMb2147, PPE37, len: 464 aa. Equivalent to Rv2123,len: 473 aa, from Mycobacterium tuberculosis strain H37Rv,(97.9% identity in 473 aa overlap). PPE37 (alternate gene name: irg2), member of the Mycobacterium tuberculosis PPE family of proteins but the C-terminus is not repetitive. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 27 bp in-frame deletion leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (464 aa versus 473 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23614962362890+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2147|PPE37
MTFPMWFAVPPEVPSAWLSTGMGPGPLLAAQYTEIATELASVLAAVQASSWQGPSADRFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAASISFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFTFLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGRLTMPNTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD
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