Gene Mb2163 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepyrD
Gene length1074 bp
IdentifierMb2163
Location 2379118 bp
Protein summary information
Molecular mass37998.6 Da
Isoelectric point10.4112
Protein length357 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_002273
M. tuberculosis H37RvRv2139
Cross-references
UniProtP65909
UniProtKB/TrEMBLX2BK73, P65909
General annotation
TypeCDS
FunctionUnknown
Productprobable dihydroorotate dehydrogenase pyrd
CommentsMb2163, pyrD, len: 357 aa. Equivalent to Rv2139,len: 357 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 357 aa overlap). Probable pyrD,dihydroorotate dehydrogenase (EC 1.3.3.1); contains dihydroorotate dehydrogenase signatures 1 and 2 (PS00911,PS00912). FASTA best: PYRD_MYCLE P46727 dihydroorotate dehydrogenase (309 aa) opt: 1653, E(): 0; (82.6% identity in 304 aa overlap)
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23791182380191+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2163|pyrD
MYPLVRRLLFLIPPEHAHKLVFAVLRGVAAVAPVRRLLRRLLGPTDPVLASTVFGVRFPAPLGLAAGFDKDGTALSSWGAMGFGYAEIGTVTAHPQPGNPAPRLFRLADDRALLNRMGFNNHGARALAIRLARHRPEIPIGVNIGKTKKTPAGDAVNDYRASARMVGPLASYLVVNVSSPNTPGLRDLQAVESLRPILSAVRAETSTPVLVKIAPDLSDSDLDDIADLAVELDLAGIVATNTTVSRDGLTTPGVDRLGPGGISGPPLAQRAVQVLRRLYDRVGDRLALISVGGIETADDAWERITAGASLLQGYTGFIYGGERWAKDIHEGIARRLHDGGFGSLHEAVGSARRRQPS
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