Gene Mb2195 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameidsA2
Gene length1059 bp
IdentifierMb2195
Location 2413881 bp
Protein summary information
Molecular mass37780.9 Da
Isoelectric point6.7284
Protein length352 amino acids
Orthologs
M. tuberculosis H37RvRv2173
M. tuberculosis MTBC0mtbc0_002307
Cross-references
UniProtA0A1R3Y0E9
InterProIPR000092, IPR008949, IPR017446
UniProtKB/TrEMBLQ7TYY7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2 (GGPPSASE) (GGPP SYNTHETASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE)
CommentsMb2195, idsA2, len: 352 aa. Equivalent to Rv2173,len: 352 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 352 aa overlap). Probable idsA2,geranylgeranyl pyrophosphate synthase (EC 2.5.1.-),similar to many e.g. Q54193 geranylgeranyl pyrophosphate synthase from Streptomyces griseus (425 aa). Contains PS00723 and PS00444Polyprenyl synthetases signature 1 and 2. FASTA scores: sptr|Q54193|Q54193 GERANYLGERANYL PYROPHOSPHATE SYNTHASE (425 aa) opt: 744, E(): 0; 39.2% identity in 352 aa overlap.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24138812414939+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2195|idsA2
MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWALVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWADIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLGVFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALTQRALATLASAPINATAKAGLSELAMMAANRSA
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