Gene Mb2215c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrpD
Gene length1113 bp
IdentifierMb2215c
Location 2434664 bp
Protein summary information
Molecular mass37739.8 Da
Isoelectric point6.4033
Protein length370 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_002328
M. tuberculosis H37RvRv2192c
Cross-references
UniProtP66993
UniProtKB/TrEMBLX2BK14, P66993
General annotation
TypeCDS
FunctionUnknown
ProductProbable anthranilate phosphoribosyltransferase TrpD
CommentsMb2215c, trpD, len: 370 aa. Equivalent to Rv2192c,len: 370 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 370 aa overlap). Probable trpD,anthranilate phosphoribosyltransferase (EC 2.4.2.18) (see citation below), similar to e.g. TRPD_LACCA|P17170, (43.2% identity in 308 aa overlap). Initiation codon uncertain,gtg at 4086 in MTCY190 favoured by homology but this has no clear ribosome binding site.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24346642435776-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2215c|trpD
MALSAEGSSGGSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
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