Gene Mb2221c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemmpS3
Gene length900 bp
IdentifierMb2221c
Location 2441295 bp
Protein summary information
Molecular mass30955.0 Da
Isoelectric point4.123
Protein length299 amino acids
Orthologs
M. tuberculosis H37RvRv2198c
M. tuberculosis MTBC0mtbc0_002334
Cross-references
UniProtP65379
UniProtKB/TrEMBLX2BK45, P65379
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED MEMBRANE PROTEIN MMPS3
CommentsMb2221c, mmpS3, len: 299 aa. Equivalent to Rv2198c,len: 299 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 299 aa overlap). Probable mmpS3,conserved membrane protein (see citation below),equivalent to ML0877|mmpS3 putative membrane protein from Mycobacterium leprae (293 aa), FASTA scores: opt: 1089,E(): 1.2e-43, (69.80% identity in 308 aa overlap). Also similar to other proteins e.g. Rv3209 from Mycobacterium tuberculosis. Contains PS00499 C2 domain signature, a hydrophobic region, and a repetitive proline and threonine rich region. BELONGS TO THE MMPS FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24412952442194-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2221c|mmpS3
MSGPNPPGREPDEPESEPVSDTGDERASGNHLPPVAGGGDKLPSDQTGETDAYSRAYSAPESEHVTGGPYVPADLRLYDYDDYEESSDLDDELAAPRWPWVVGVAAIIAAVALVVSVSLLVTRPHTSKLATGDTTSSAPPVQDEITTTKPAPPPPPPAPPPTTEIPTATETQTVTVTPPPPPPPATTTAPPPATTTTAAAPPPTTTTPTGPRQVTYSVTGTKAPGDIISVTYVDAAGRRRTQHNVYIPWSMTVTPISQSDVGSVEASSLFRVSKLNCSITTSDGTVLSSNSNDGPQTSC
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