Gene Mb2225c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameadok
Gene length975 bp
IdentifierMb2225c
Location 2446200 bp
Protein summary information
Molecular mass34472.1 Da
Isoelectric point4.5121
Protein length324 amino acids
Orthologs
M. tuberculosis H37RvRv2202c
M. tuberculosis MTBC0mtbc0_002338
Cross-references
UniProtP83736
UniProtKB/TrEMBLX2BK30, P83736
General annotation
TypeCDS
FunctionUnknown
Productadenosine kinase
CommentsMb2225c, cbhK, len: 324 aa. Equivalent to Rv2202c,len: 324 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 324 aa overlap). Probable cbhK,carbohydrate kinase (but not ribose) (EC 2.7.-.-), similar to several e.g. AE000915_1 Methanobacterium thermoautotrop (309 aa) FASTA score: opt: 370, E(): 3.3e-18; 31.2% identity in 276 aa overlap. Low similarity to carbohydrate kinases, e.g. SW:RBSK_BACSU P36945 ribokinase (23.9% identity in 272 aa overlap); contains PS00583 pfkB family of carbohydrate kinases signature 1
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24462002447174-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2225c|adok
MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDYEAAASRLAGAYGEHAAAEIVAVLA
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