Gene Mb2249 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepanB
Gene length846 bp
IdentifierMb2249
Location 2476889 bp
Protein summary information
Molecular mass29336.4 Da
Isoelectric point5.885
Protein length281 amino acids
Orthologs
M. tuberculosis H37RvRv2225
M. tuberculosis MTBC0mtbc0_002363
Cross-references
UniProtP0C2T4
UniProtKB/TrEMBLX2BKH7, P0C2T4
General annotation
TypeCDS
FunctionUnknown
Product3-methyl-2-oxobutanoate hydroxymethyltransferase panb
CommentsMb2249, panB, len: 281 aa. Equivalent to Rv2225,len: 281 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 281 aa overlap). Probable panB,3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11), similar to PANB_ECOLI|P31057 3-methyl-2-oxobutanoate hydroxymethyltransferase from Escherichia coli (45.9% identity in 257 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24768892477734+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2249|panB
MSEQTIYGANTPGGSGPRTKIRTHHLQRWKADGHKWAMLTAYDYSTARIFDEAGIPVLLVGDSAANVVYGYDTTVPISIDELIPLVRGVVRGAPHALVVADLPFGSYEAGPTAALAAATRFLKDGGAHAVKLEGGERVAEQIACLTAAGIPVMAHIGFTPQSVNTLGGFRVQGRGDAAEQTIADAIAVAEAGAFAVVMEMVPAELATQITGKLTIPTVGIGAGPNCDGQVLVWQDMAGFSGAKTARFVKRYADVGGELRRAAMQYAQEVAGGVFPADEHSF
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