Gene Mb2265 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaceE
Gene length2706 bp
IdentifierMb2265
Location 2491687 bp
Protein summary information
Molecular mass100316.0 Da
Isoelectric point5.9175
Protein length901 amino acids
Orthologs
M. tuberculosis H37RvRv2241
M. tuberculosis MTBC0mtbc0_002383
Cross-references
UniProtA0A1R3Y0S8
InterProIPR004660, IPR005474, IPR009014
UniProtKB/TrEMBLQ7TYW7
General annotation
TypeCDS
FunctionUnknown
Productpyruvate dehydrogenase e1 component acee (pyruvate decarboxylase) (pyruvate dehydrogenase) (pyruvic dehydrogenase)
CommentsMb2265, aceE, len: 901 aa. Equivalent to Rv2241,len: 901 aa, from Mycobacterium tuberculosis strain H37Rv,(99.9% identity in 901 aa overlap). Probable aceE,pyruvate dehydrogenase E1 component (EC 1.2.4.1), similar to others e.g. ODP1_ECOLI|P06958 pyruvate dehydrogenase E1 component from Escherichia coli, FASTA score: (51.2% identity in 891 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24916872494392+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2265|aceE
MASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDRALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA
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