Gene Mb2273c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglpD1
Gene length1551 bp
IdentifierMb2273c
Location 2502304 bp
Protein summary information
Molecular mass54176.0 Da
Isoelectric point9.5135
Protein length516 amino acids
Orthologs
M. tuberculosis H37RvRv2249c
M. tuberculosis MTBC0mtbc0_002391
Cross-references
UniProtP64183
UniProtKB/TrEMBLX2BK71, P64183
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLPD1
CommentsMb2273c, glpD1, len: 516 aa. Equivalent to Rv2249c,len: 516 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 516 aa overlap). Probable glpD1,glycerol-3-phosphate dehydrogenase, similar to SW:GLPD_ECOLI P13035 aerobic glycerol-3-phosphate dehydrogenase (30.0% identity in 486 aa overlap) and SW:GLPA_ECOLI P13032 anaerobic glycerol-3-phosphate dehydrogenase (28.2% identity in 504 aa overlap). Also similar to Rv3302c|glpD2 glycerol-3-phosphate dehydrogenase. COFACTOR: FAD (BY SIMILARITY). BELONGS TO THE FAD-DEPENDENT GLYCEROL-3-PHOSPHATE DEHYDROGENASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25023042503854-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2273c|glpD1
MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDLAFGTSRWSSKLVHGGLRYLASGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMGHTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVVEIAPTVRRDGLDGGLLAYDGQLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAGVWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGLTDEDAPGPIPDVPQPSSEEITFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQGRTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRAITLRHLRAAKCRTRNLPLIGAPANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTHEGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR
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