Gene Mb2274c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2274c
Gene length570 bp
IdentifierMb2274c
Location 2503848 bp
Protein summary information
Molecular mass20449.5 Da
Isoelectric point7.5115
Protein length189 amino acids
Orthologs
M. tuberculosis H37RvRv2250c
M. tuberculosis MTBC0mtbc0_002392
Cross-references
UniProtQ7VEN0
UniProtKB/TrEMBLX2BKJ2, Q7VEN0
General annotation
TypeCDS
FunctionUnknown
ProductPossible transcriptional regulatory protein
CommentsMb2274c, -, len: 189 aa. Equivalent to Rv2250c,len: 189 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 189 aa overlap). Possible transcriptional regulatory protein, TetR family. Start unclear; ORF has been shortened since first submission to avoid overlap with Rv2251 (-30 aa). Contains probable helix-turn-helix motif (Score 2243, +6.70 SD)
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25038482504417-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2274c|Mb2274c
MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC
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