Gene Mb2291c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecyp128
Gene length1470 bp
IdentifierMb2291c
Location 2521761 bp
Protein summary information
Molecular mass53313.1 Da
Isoelectric point9.3794
Protein length489 amino acids
Orthologues
M. tuberculosisRv2268c
Cross-references
UniProtP63714
UniProtKB/TrEMBLX2BKL8, P63714
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CYTOCHROME P450 128 CYP128
CommentsMb2291c, cyp128, len: 489 aa. Equivalent to Rv2268c, len: 489 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 489 aa overlap). Probable cyp128, cytochrome P450 (EC 1.14.-.-), similar to (but longer than) cytochrome p-450 e.g. CPXK_SACER P3 3271 cytochrome p-450 107b1 (405 aa), FASTA scores, opt: 620,E(): 8.3e-33, (31.8% identity in 406 aa overlap); contains PS00086 Cytochrome P450 cysteine heme-iron ligand signature, similar to MTCY50.26, 32.7% identity in 382 aa overlap
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25217612523230-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2291c|cyp128
MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRRRASSGGIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLTDFDPFDPAIAADPYPHYRELLAGERVQYNPKRDVYILSRYADVREAARNHDTLSSARGVTFSRGWLPFLPTSDPPAHTRMRKQLAPGMARGALETWRPMVDQLARELVGGLLTQTPADVVSTVAAPMPMRAITSVLGVDGPDEAAFCRLSNQAVRITDVALSASGLISLVQGFAGFRRLRALFTHRRDNGLLRECTVLGKLATHAEQGRLSDDELFFFAVLLLVAGYESTAHMISTLFLTLADYPDQLTLLAQQPDLIPSAIEEHLRFISPIQNICRTTRVDYSVGQAVIPAGSLVLLAWGAANRDPRQYEDPDVFRADRNPVGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDRIEVVEPPTWTTNANLRGLTRLRVAVTPRVAP
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