Gene Mb2299 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecyp121
Gene length1191 bp
IdentifierMb2299
Location 2526703 bp
Protein summary information
Molecular mass43256.0 Da
Isoelectric point6.6392
Protein length396 amino acids
Cross-references
UniProtP0A515
UniProtKB/TrEMBLX2BJT7, P0A515
General annotation
TypeCDS
FunctionUnknown
ProductCytochrome P450 121 CYP121
CommentsMb2299, cyp121, len: 396 aa. Equivalent to Rv2276,len: 396 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 396 aa overlap). cyp121, cytochrome P450 (EC 1.14.-.-) (see citation below), similar to e.g. G303644 (397 aa) opt: 675, z-score: 776.4, E(): 2.7e-36,(33.7% identity in 407 aa overlap); contains PS00086 Cytochrome P450 cysteine heme-iron ligand signature,similar to MTCY339.42, 29.2% identity in 298 aa overlap.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25267032527893+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2299|cyp121
MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW
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