Gene Mb2350c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2350c
Gene length909 bp
IdentifierMb2350c
Location 2572956 bp
Protein summary information
Molecular mass32989.6 Da
Isoelectric point6.0299
Protein length302 amino acids
Orthologs
M. tuberculosis H37RvRv2323c
M. tuberculosis MTBC0mtbc0_002471
Cross-references
UniProtA0A1R3Y0X5
InterProIPR003198
UniProtKB/TrEMBLQ7TYT7
General annotation
TypeCDS
FunctionUnknown
Productconserved protein
CommentsMb2350c, -, len: 302 aa. Equivalent to Rv2323c,len: 302 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 302 aa overlap). Conserved hypothetical protein, highly similar to others eg Q9FC91|2SCG58.22 CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor (288 aa), FASTA scores: opt: 561, E(): 7.3e-28,(46.95% identity in 279 aa overlap); P74535|SLL1336 HYPOTHETICAL 78.3 KDA PROTEIN from Synechocystis sp. (705 aa), FASTA scores: opt: 555, E(): 2.1e-27, (37.75% identity in 265 aa overlap); etc. Also similar to various hydrolases e.g. Q53797 BETA-HYDROXYLASE (BLEOMYCIN/PHLEOMYCIN BINDING PROTEIN, ANKYRIN HOMOLOGUE,BLEOMYCIN AND TRANSPORT PROTEIN) from Streptomyces verticillus (326 aa), FASTA scores: opt: 211, E(): 4.5e-06, (26.75% identity in 303 aa overlap); Q9X7M4|DDAH_STRCO|SC5F2A.01c NG,NG-dimethylarginine dimethylaminohydrolase (EC 3.5.3.18) (Dimethylargininase) (Dimethylarginine dimethylaminohydrolase) (258 aa), FASTA scores: opt: 209, E(): 4.9e-06, (27.15% identity in 243 aa overlap); G434715 beta-hydroxylase (bleomicin/phleomycin binding protein) from Streptomyces verticillus (326 aa),FASTA scores: opt: 211, E(): 4.5e-06, (26.75% identity in 303 aa overlap); etc.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25729562573864-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2350c|Mb2350c
MENTQRPSFDCEIRAKYRWFMTDSYVAAARLGSPARRTPRTRRYAMTPPAFFAVAYAINPWMDVTAPVDVQVAQAQWEHLHQTYLRLGHSVDLIEPISGLPDMVYTANGGFITHDIAVVARFRFPERAGESRAYASWMSSVGYRPVTTRHVNEGQGDLLMVGERVLAGYGFRTDQRAHAEIAAVLGLPVVSLELVDPRFYHLDTALAVLDDHTIAYYPPAFSTAAQEQLSALFPDAIVVGSADAFVFGLNAVSDGLNVVLPVAAMGFAAQLRAAGFEPVGVDLSELLKGGGSVKCCTLEIHP
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