Gene Mb2377c in Mycobacterium bovis AF2122/97
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE40
Gene length1845 bp
IdentifierMb2377c
Location 2605762 bp
Protein summary information
Molecular mass58319.4 Da
Isoelectric point3.6702
Protein length614 amino acids
Orthologs
M. tuberculosis H37RvRv2356c
M. tuberculosis MTBC0mtbc0_002508
Cross-references
UniProtA0A1R3Y0Z4
InterProIPR000030, IPR002989
UniProtKB/TrEMBLQ7TYR8
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe40
CommentsMb2377c, PPE40, len: 614 aa. Equivalent to Rv2356c,len: 615 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 615 aa overlap). Member of Mycobacterium tuberculosis PPE_family, highly similar to others e.g. Q10778|MTCY48.17|YF48_MYCTU HYPOTHETICAL PPE-FAMILY PROTEIN (678 aa), FASTA scores: opt: 1888, E(): 1.9e-78, (54.4% identity in 667 aa overlap); Q10540|MTCY31.06c, E241779|MTCY98, P42611|MTV037.06c,Q10813|MTCY274.23c, P71657|MTCY02B10.25c, MTCY03C7.23,P71869|MTCY03C7.24c, etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 3 bp deletion (gcg-*) leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (614 aa versus 615 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26057622607606-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2377c|PPE40
MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGASAAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNTGFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR
Bibliography
No article yet recorded