Gene Mb2382c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | LONG (C50) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-DECAPRENYL DIPHOSPHATE SYNTHASE) |
| Comments | Mb2382c, -, len: 296 aa. Equivalent to Rv2361c,len: 296 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 296 aa overlap). Long (C50) chain Z-isoprenyl diphosphate synthase (EC 2.5.1.-) (see citation below), equivalent to UPPS_MYCLE|ML0634|B1937_F2_65|P38119 UNDECAPRENYL PYROPHOSPHATE SYNTHETASE from Mycobacterium leprae (296 aa), FASTA scores: opt: 1789, E(): 1.8e-97, (86.5% identity in 296 aa overlap). Also highly similar to others e.g. UPPS|Q9L2H4 UNDECAPRENYL PYROPHOSPHATE SYNTHETASE from Streptomyces coelicolor (277 aa), FASTA scores: opt: 1098, E(): 8.2e-60, (63.5% identity in 247 aa overlap); Q55482|UPPS_SYNY3|SLL0506 from Synechocystis sp. strain PCC 6803 (249 aa), FASTA scores: opt: 686, E(): 4.2e-33,(46.4% identity in 235 aa overlap); O67291|UPPS_AQUAE|AQ_1248 from Aquifex aeolicus (231 aa),FASTA scores: opt: 684, E(): 5.2e-33, (46.3% identity in 229 aa overlap); etc. Also similar to Rv1086|MTV017.39 from Mycobacterium tuberculosis. Contains PS01066 Hypothetical YBR002c family signature. SEEMS TO BELONG TO THE UPP SYNTHETASE FAMILY. Note that previously known as uppS. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2610649 | 2611539 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2382c|Mb2382c
MARDARKRTSSNFPQLPPAPDDYPTFPDTSTWPVVFPELPAAPYGGPCRPPQHTSKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVRRRRDTLKKLGVRIRWVGSRPRLWRSVINELAVAEEMTKSNDVITINYCVNYGGRTEITEATREIAREVAAGRLNPERITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRTRRFGSA
Bibliography
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