Gene Mb2385c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE GTP-BINDING PROTEIN ERA |
| Comments | Mb2385c, era, len: 300 aa. Equivalent to Rv2364c,len: 300 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 300 aa overlap). Probable era,GTP-binding protein, equivalent to Q49768|ERA_MYCLE|ML0631|B1937_F3_102 GTP-BINDING PROTEIN ERA HOMOLOG from Mycobacterium leprae (300 aa) FASTA scores: opt: 1589, E(): 3.4e-88, (81.4% identity in 301 aa overlap). Also highly similar to other GTP-binding proteins e.g. Q9RDF2|ERA_STRCO|SCC77.06 from Streptomyces coelicolor (317 aa), FASTA scores: opt: 1264, E(): 1.1e-68, (64.0% identity in 306 aa overlap); Q9KD52|ERA_BACHD|BH1367|BEX from Bacillus halodurans (304 aa), FASTA scores: opt: 869, (44.8% identity in 297 aa overlap); Q9KIH7|ERA_LACLA|ERAL from Lactococcus lactis (subsp. lactis) (Streptococcus lactis), and Lactococcus lactis (subsp. cremoris) (Streptococcus cremoris) (303 aa), FASTA scores: opt: 781, E(): 9.4e-40, (40.25% identity in 298 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ERA/TRME FAMILY OF GTP-BINDING PROTEINS, ERA SUBFAMILY. Note that previously known as bex. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2613842 | 2614744 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2385c|era
MTEFHSGFVCLVGRPNTGKSTLTNALVGAKVAITSTRPQTTRHAIRGIVHSDDFQIILVDTPGLHRPRTLLGKRLNDLVRETYAAVDVIGLCIPADEAIGPGDRWIVEQLRSTGPANTTLVVIVTKIDKVPKEKVVAQLVAVSELVTNAAEIVPVSAMTGDRVDLLIDVLAAALPAGPAYYPDGELTDEPEEVLMAELIREAALQGVRDELPHSLAVVIDEVSPREGRDDLIDVHAALYVERDSQKGIVIGKGGARLREVGTAARSQIENLLGTKVYLDLRVKVAKNWQRDPKQLGRLGF
Bibliography
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