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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb2387c, -, len: 435 aa. Equivalent to Rv2366c,len: 435 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 435 aa overlap). Probable conserved transmembrane protein, highly similar to Q9L2L3|SCC117.07 PUTATIVE MEMBRANE PROTEIN from Streptomyces coelicolor (358 aa), FASTA scores: opt: 1159, E(): 5.5e-64, (53.0% identity in 353 aa overlap); ans similar to hypothetical proteins and hemolysin-related proteins e.g. Q9HN02|HLP|VNG2308G HEMOLYSIN PROTEIN from Halobacterium sp. strain NRC-1 (457 aa), FASTA scores: opt: 623, E(): 6.2e-31, (28.4% identity in 433 aa overlap); etc. Potential transmembrane protein with 2 CBS domains. BELONGS TO THE UPF0053 FAMILY.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26151312616438-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2387c|Mb2387c
MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLRKVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMVLASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNALTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPAREVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYLKDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSARLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLHAEGGTDHRGRVRIGTVLLSPAEPDGADDEEADHPG
      
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