Gene Mb2399c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | LYSINE-N-OXYGENASE MBTG (L-LYSINE 6-MONOOXYGENASE) (LYSINE N6-HYDROXYLASE) |
| Comments | Mb2399c, mbtG, len: 431 aa. Equivalent to Rv2378c,len: 431 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 431 aa overlap). mbtG, lysine-N -oxygenase (hydroxylase) (EC 1.14.13.59) showing some similarity with various proteins including ornithine and lysine-N-oxygenases, e.g. Q9K6Q1|TRKA|BH3677 POTASSIUM UPTAKE PROTEIN from Bacillus halodurans (350 aa), FASTA scores: opt: 153, E(): 0.016, (25.2% identity in 246 aa overlap); P56584|SID1_USTMA L-ORNITHINE 5-MONOOXYGENASE (EC 1.13.12.-) from Ustilago maydis (Smut fungus) (570 aa), FASTA scores: opt: 136, E(): 0.31, (22.85% identity in 127 aa overlap); Q9HHV0|HXYA|VNG6214G MONOOXYGENASE from Halobacterium sp. strain NRC-1 (477 aa), FASTA scores: opt: 119, E(): 3.4, (40.0% identity in 70 aa overlap); O69828|SC1A6.23 PUTATIVE LYSINE N-HYDROXLASE (FRAGMENT) from Streptomyces coelicolor (134 aa), BLAST score: 76 (similarity in part for this one); etc. COFACTORS: FAD (BY SIMILARITY). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2624479 | 2625774 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2399c|mbtG
MNPTLAVLGAGAKAVAVAAKASVLRDMGVDVPDVIAVERIGVGANWQASGGWTDGAHRLGTSPEKDVGFPYRSALVPRRNAELDERMTRYSWQSYLIATASFAEWIDRGRPAPTHRRWSQYLAWVADHIGLKVIHGEVERLAVTGDRWALCTHETTVQADALMITGPGQAEKSLLPGNPRVLSIAQFWDRAAGHDRINAERVAVIGGGETAASMLNELFRHRVSTITVISPQVTLFTRGEGFFENSLFSDPTDWAALTFDERRDALARTDRGVFSATVQEALLADDRIHHLRGRVAHAVGRQGQIRLTLSTNRGSENFETVHGFDLVIDGSGADPLWFTSLFSQHTLDLLELGLGGPLTADRLQEAIGYDLAVTDVTPKLFLPTLSGLTQGPGFPNLSCLGLLSDRVLGAGIFTPTKHNDTRRSGEHQSFR
Bibliography
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