Gene Mb2403c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POLYKETIDE SYNTHETASE MBTC (POLYKETIDE SYNTHASE) |
| Comments | Mb2403c, mbtC, len: 444 aa. Equivalent to Rv2382c,len: 444 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 444 aa overlap). mbtC, polyketide synthase (see citations below), similar in part to several synthases e.g. Q9F7T9 AVERMECTIN POLYKETIDE SYNTHASE (FRAGMENT) from Streptomyces avermitilis (3626 aa), FASTA scores: opt: 1458, E(): 7e-82, (50.65% identity in 446 aa overlap); AAG23264|SPNA POLYKETIDE SYNTHASE LOADING AND EXTENDER MODULE 1 from Saccharopolyspora spinosa (2595 aa) FASTA scores: opt: 1441, E(): 6e-81, (49.1% identity in 446 aa overlap); O33954|TYLG TYLACTONE SYNTHASE STARTER MODULE AND MODULES 1 & 2 from Streptomyces fradiae (4472 aa) FASTA scores: opt: 1439, E(): 1.2e-80, (51.0% identity in 447 aa overlap); O30764|NIDA1 POLYKETIDE SYNTHASE MODULES 1 AND 2 from Streptomyces caelestis (4340 aa) FASTA scores: opt: 1432, E(): 3.3e-80, (50.9% identity in 442 aa overlap); etc. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2638340 | 2639674 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2403c|mbtC
MSDNDPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGFKPIHNLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHDVGCYVGASALEYGPALTEFSHHSGHLITGTSLGVISGRIAYTLDLAGPALTVDTSCSSALAAFHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWAEGAAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAVVPADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVKVILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNSHVIVSMPDTVSAPERGPECGEV
Bibliography
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