Gene Mb2418 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS41
Gene length1083 bp
IdentifierMb2418
Location 2660871 bp
Protein summary information
Molecular mass30653.0 Da
Isoelectric point3.8507
Protein length360 amino acids
Cross-references
InterProIPR000084
UniProtKB/TrEMBLQ7TYP1
SWISS-MODELA0A1R3Y109
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs41
CommentsMb2418, PE_PGRS41, len: 360 aa. Equivalent to Rv2396, len: 361 aa, from Mycobacterium tuberculosis strain H37Rv, (99.2% identity in 361 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, highly similar to many e.g. AAK47132|MT2812 PE_PGRS family protein from Mycobacterium tuberculosis strain CDC1551 (454 aa), FASTA scores: opt: 1256, E(): 2.4e-44, (56.0% identity in 377 aa overlap); AAK46139|MT1866 PE_PGRS FAMILY PROTEIN from M. tuberculosis strain CDC1551 (491 aa), FASTA scores: opt: 1250, E(): 4.4e-44, (57.8% identity in 372 aa overlap); Y278_MYCTU|Rv0278C|MTV035.06c HYPOTHETICAL PE-PGRS FAMILY PROTEIN (957 aa), FASTA scores: opt: 1253, E(): 5.2e-44,(55.5% identity in 400 aa overlap); P71664|Rv1396c|MTCY21B4.13c HYPOTHETICAL GLYCINE-RICH 47.9 KDA PROTEIN (576 aa), FASTA scores: opt: 1236, E(): 1.8e-43, (55.55% identity in 402 aa overlap); etc. Contains PS00583 pfkB family of carbohydrate kinases signature 1. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 3 bp deletion (gcc-*) leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (360 aa versus 361 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26608712661953+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2418|PE_PGRS41
MSFLIASPEALAATATYLTGIGSAINAANAVAAAPTTEILAAGTDEVSTAISALFGAHAQAYQALSAHVAAFHDQFVHTLTAGAGSYMAAEAAASPLQALQLELLNAINAPTLALLGRPLIGDGTDAAPGSGGAGGAGGILIGNGGTGGASDLAGTGRGGVGGAGGAGGLFGIGGAGGGCGSAVAIGGDGGAGGAGGVFSGGGAGGAGDAIGGSGGAGGTGGLLGGGGGAGGAGGAGGNGGGASNSASIGGDGGSGGAGGMLYGAGGVGGNGGAAVAIGGDGGAGGRAGAIGNGGDGGNGGTSNTPGGSGGDGGNGGNAGLIGSGGNGGNAEIVISGGSVAGTGGNGGLLLGFNGTNGLP
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