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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productglucosyl-3-phosphoglycerate phosphatase gpgp
CommentsMb2442c, -, len: 223 aa. Equivalent to Rv2419c,len: 223 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 223 aa overlap). Probable phosphoglycerate mutase (EC 5.4.2.1), equivalent to Q9CC00|ML1452 POSSIBLE PHOSPHOGLYCERATE MUTASE from Mycobacterium leprae (224 aa), FASTA scores: opt: 1206,E(): 8.8e-68, (80.35% identity in 224 aa overlap). Also highly similar to Q9RDL0|SCC123.14c PUTATIVE PHOSPHOGLYCERATE MUTASE from Streptomyces coelicolor (223 aa), FASTA scores: opt: 431, E(): 9.4e-20, (40.85% identity in 213 aa overlap); and similar to others e.g. Q9RVD2|DR1097 from Deinococcus radiodurans (232 aa), FASTA scores: opt: 291, E(): 4.6e-11, (39.3% identity in 173 aa overlap); etc. Some similarity to Q10512|Rv2228c|Y019_MYCTU|MT2287|MTcy427.09c hypothetical 39.2 kd protein from Mycobacterium tuberculosis (364 aa) FASTA scores: opt: 196, E(): 2.8e-06, (45.6% identity in 79 aa overlap). Contains PS00175 Phosphoglycerate mutase family phosphohistidine signature. BELONGS TO THE PHOSPHOGLYCERATE MUTASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26853132685984-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2442c|gpgp
MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQPLLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWGGADEPDRPVVLVAHGGLIAVLSAALLKLPVANWPALGGMGNASWTQLSGHWAPGSDFESIRWRLDVWNASAQVSSDVL
      
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