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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GTP1/OBG-FAMILY GTP-BINDING PROTEIN OBG
CommentsMb2467c, obg, len: 479 aa. Equivalent to Rv2440c,len: 479 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 479 aa overlap). Probable obg,nucleotide-binding protein, equivalent to Q9CBZ4|ML1465 GTP1/OBG-FAMILY GTP-BINDING PROTEIN from Mycobacterium leprae (478 aa), FASTA scores: opt: 1328, E(): 8.4e-70,(58.9% identity in 479 aa overlap). Also highly similar to others e.g. P95722|OBG GTP-BINDING PROTEIN from Streptomyces coelicolor (478 aa), FASTA scores: opt: 1311,E(): 8.2e-69, (60.7% identity in 476 aa overlap); P20964|OBG_BACSU SPO0B-ASSOCIATED GTP-BINDING PROTEIN from Bacillus subtilis (428 aa), FASTA scores: opt: 1006, E(): 3.9e-51, (42.9% identity in 436 aa overlap); Q9KDK0|OBG|BH1213 GTP-BINDING PROTEIN INVOLVED IN INITIATION OF SPORULATION from Bacillus halodurans (427 aa), FASTA scores: opt: 978, E(): 1.7e-49, (41.95% identity in 436 aa overlap); etc. Highly similar (identical but shorter 5 aa) to AAK46813|MT2516 GTP-BINDING PROTEIN from Mycobacterium tuberculosis strain CDC1551 (484 aa), FASTA scores: opt: 3205, E(): 7.9e-179,(100% identity in 479 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE GTP1/OBG FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27064102707849-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2467c|obg
MPRFVDRVVIHTRAGSGGNGCASVHREKFKPLGGPDGGNGGRGGSIVFVVDPQVHTLLDFHFRPHLTAASGKHGMGNNRDGAAGADLEVKVPEGTVVLDENGRLLADLVGAGTRFEAAAGGRGGLGNAALASRVRKAPGFALLGEKGQSRDLTLELKTVADVGLVGFPSAGKSSLVSAISAAKPKIADYPFTTLVPNLGVVSAGEHAFTVADVPGLIPGASRGRGLGLDFLRHIERCAVLVHVVDCATAEPGRDPISDIDALETELACYTPTLQGDAALGDLAARPRAVVLNKIDVPEARELAEFVRDDIAQRGWPVFCVSTATRENLQPLIFGLSQMISDYNAARPVAVPRRPVIRPIPVDDSGFTVEPDGHGGFVVSGARPERWIDQTNFDNDEAVGYLADRLARLGVEEELLRLGARSGCAVTIGEMTFDWEPQTPAGEPVAMSGRGTDPRLDSNKRVGAAERKAARSRRREHGDG
      
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