Gene Mb2471c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE RIBONUCLEASE E RNE |
| Comments | Mb2471c, rne, len: 953 aa. Equivalent to Rv2444c,len: 953 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 953 aa overlap). Possible rne,ribonuclease E (EC 3.1.-.-), highly similar to others e.g. Q9CBZ1|ML1468 POSSIBLE RIBONUCLEASE from Mycobacterium leprae (924 aa), FASTA scores: opt: 3713, E(): 2.4e-174,(74.2% identity in 966 aa overlap); Q9SI08|AT2G04270 PUTATIVE RIBONUCLEASE E from Arabidopsis thaliana (502 aa), FASTA scores: opt: 674, E(): 7.5e-26, (31.2% identity in 410 aa overlap); etc. Similar at C-terminal end to P21513|RNE_ECOLI|AMS|HMP1|B1084 ribonuclease E (EC 3.1.4.-) (RNASE E) from Escherichia coli strain K12 (1061 aa), FASTA scores: opt: 554, E(): 9.9e-20, (37.8% identity in 386 aa overlap). Also similar in medium part to several cytoplasmic axial filament proteins e.g. Q9HVU4|CAFA|PA4477 from Pseudomonas aeruginosa (485 aa),FASTA scores: opt: 664, E(): 2.3e-25, (42.8% identity in 418 aa overlap); etc. Equivalent to AAK46818 from Mycobacterium tuberculosis strain CDC1551 (621 aa) but longer 332 aa in N-terminal part. SEEMS TO BELONG TO THE RNE FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2710286 | 2713147 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2471c|rne
MIDGAPPSDPPEPSQHEELPDRLRVHSLARTLGTTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHLETAGVLAASVHAPEASEEPESRLMLETQETRNADVERPHYMPLFVAPQPIPEPLADDEDVDDGPDYVADDSDADDEGQLDRPANRRRRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAETDDGDDRDSEDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAALEGPLPDDPPNTVVHERVPRAGDKAGNSQDGGSGSTEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLAGRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEEPDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYESADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPNCSGRGILLHADPVDSAAATGRKSEPGARRGKRSKKSRSEESSDRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGDEESGEPAAELAEQAGDQPPTDLDDTAQADFEDTEDTDEDEDELDADEDLEDLDDEDLDEDLDVEDSDSDDEDSDEDAADADVDEEDAAGLDGSPGEVDVPGVTELAPTRPRRRVAGRPAGPPIRLD
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